![]() Second paragraph: you should concisely explain what was done, the main findings and why they are significant.Then briefly explain the background to your study, the question you sought out to answer and why. First paragraph: include the title of your manuscript and the type of manuscript it is (e.g.Include the date of submission and the journal you are submitting to. If known, address the editor who will be assessing your manuscript by their name.The following structure covers all the necessary points that need to be included. Then, write a letter that explains why the editor would want to publish your manuscript. disclosures, statements, potential reviewers). Instead, check to see whether the journal’s Instructions for Authors have any cover letter requirements (e.g. Please let me know of your decision at your earliest convenience. We would like to have the manuscript considered for publication in Pathobiology. I am sending you our manuscript entitled “Large Scale Analysis of Cell Cycle Regulators in bladder cancer” by Researcher et al. ![]() The following is an example of a poor cover letter: As such it is worth spending time writing a coherent and persuasive cover letter. As well as introducing your work to the editor you can also take this opportunity to explain why the manuscript will be of interest to a journal's readers, something which is always as the forefront editors’ mind. A good cover letter can help to “sell” your manuscript to the journal editor.
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